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Sleep Well Advanced

$19.95 /  Pack of 30 Vcaps 

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Counter jet lag effects when traveling.

Key Features
  • Promote restful sleep*
  • Helps fall asleep faster*
  • Improves sleep quality*
Recommended
  • In disrupted and restless sleep situations (tossing and turning or feeling only half-sleep
  • To counteract the undesirable effects of jet lag
Intake
  • For adults, take 1 vegan capsule with water, preferably close to bedtime.
Travel pack
  • 3 blisters of 10 vegan capsules, designed for all climate zones

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Sleep Well Advanced, natural dietary supplement with Melatonin, Valerian Root (Valeriana officinalis), Magnesium (as Magnesium Bisglycinate Chelate)

Safety Information

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  • SUPPLEMENT FACTS

    Serving size 1 vegan capsule • Servings per container 30 capsules

    Amount per serving %NRV*
    Magnesium (as Magnesium Bisglycinate Chelate) 20 mg 5%
    Valerian Root Extract (Valeriana officinalis) 0.8% Valerenic Acids 200 mg -
    Melatonin 5 mg -

    *Nutritional Reference Value; - NRV not established

    Hypromellose and purple carrot concentrate (capsule shell), microcrystalline cellulose, hydroxypropyl cellulose, ascorbyl palmitate.

    Recommended Intake

    For adults, take 1 vegan capsule with water, preferably close to bedtime. Intended for occasional/intermittent use only.

    Warning
    • Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.
    • Do not exceed the stated recommended daily dose.
    • The product should be stored out of reach of young children.
    • Do not use if you are pregnant or while breastfeeding.
    • If you have any medical condition, consult a healthcare practitioner before taking any food supplement.
    • Store in a cool and dry place.
    Disclaimer

    These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

  • INGREDIENTS
    MELATONIN

    Melatonin is a natural hormone produced in the brain at night, also present in plants and other living beings. In humans, it regulates the sleep–wake cycle and helps synchronize circadian rhythms, the body’s 24-hour internal clock. Its production rises in the evening to signal rest and declines with morning light. Stress, aging, and artificial light can disrupt this rhythm, making it harder to fall asleep. Supplementation helps restore balance, supporting faster sleep onset, better quality, and refreshed mornings, while also acting as a gentle antioxidant—without risk of dependence.

    VALERIAN

    Valerian (Valeriana officinalis L.) is a perennial plant native to Europe and Asia, also cultivated in North America. Its root has been valued since ancient Greece and Rome, where Hippocrates and Galen described its calming use for insomnia and nervous tension. Key compounds include valerenic acids, valepotriates, and volatile oils, which may act on GABA pathways. Today, valerian is widely used in phytomedicine to promote relaxation and improve sleep quality.

    MAGNESIUM

    Magnesium bisglycinate is a highly absorbable form of magnesium, an essential mineral involved in over 300 enzymatic reactions, including those affecting the nervous and muscular systems. It supports relaxation by modulating GABA activity and easing muscle tension, helping reduce nighttime restlessness. Deficiency has been linked to poor sleep quality and insomnia, while supplementation may promote deeper, more restorative sleep.

  • SCIENTIFIC EVIDENCE
    WHY IS SLEEP WELL ADVANCED IDEAL FOR TRAVELERS AND JET LAG?

    Melatonin is the body’s key regulator of circadian rhythms and the sleep–wake cycle. Its secretion normally rises in the evening, but exposure to light at night and rapid time-zone changes can disrupt this pattern, leading to jet lag. Clinical trials and meta-analyses show that melatonin supplementation reduces sleep latency, improves total sleep time, and helps realign circadian rhythms after travel.1,2

    Valerian (Valeriana officinalis) root has calming properties that support relaxation when external stress, noise, or anxiety interfere with rest — common issues when sleeping in hotels or airplanes. Its bioactive compounds interact with GABA pathways to ease nervous tension. Systematic reviews suggest valerian may improve subjective sleep quality and make falling asleep in new environments easier.3,4

    Magnesium bisglycinate is a highly absorbable form of magnesium, important for both nervous and muscular relaxation. Travel can cause fatigue, restlessness, or muscle tension due to long flights and irregular schedules. Clinical studies show magnesium supplementation improves sleep efficiency and reduces nighttime awakenings, supporting more restorative rest when routines are disrupted.5,6

    References

    1 Ferracioli-Oda E., et al. (2013). Meta-analysis: Melatonin for the treatment of primary sleep disorders.PLoS One,  Res.,8(5), e63773.
    2 Li T., et al. (2019). Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis. Front. Neuroendocrinol.,52, 22–28.
    3 Bent S., et al. (2006). Valerian for sleep: A systematic review and meta-analysis. Am J Med.,119(12), 1005–1012.
    4 Fernández-San-Martín M. I., et al. (2010). Effectiveness of Valerian on insomnia: a meta-analysis of randomized placebo-controlled trials. Sleep Med, 11(6), 505–511.
    5 Abbasi B., et al. (2012). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci., 17(12), 1161–1169.
    6 Rondanelli M., et al. (2011). The effect of oral magnesium supplementation on insomnia in elderly subjects: a randomized controlled clinical trial. Magnes Res., 17(12), 24(2), 85–92.

What is Melatonin?

Melatonin is a hormone naturally produced by the pineal gland responsible for regulating the sleep cycle.

Melatonin

Therapeutic use

Melatonin is a hormone known for its ability to regulate chronobiological rhythms and improve sleep. Secreted by the pineal gland or epiphysis, it is stimulated by the absence or decrease of light and is inhibited by exposure to light. The concentration of available melatonin tends to decrease with age, which can lead to difficulty falling asleep and insomnia. Taking melatonin in people with regular and stable sleep is of limited interest.

Melatonin is especially recommended for people who travel frequently and change time zones. An intercontinental trip may interfere with sleep cycles, for those people who often suffer from jet lag symptoms. In this case, taking melatonin can help improve sleep, both to help fall asleep and to increase sleep duration. Melatonin can also be interesting for people working at night with irregular work cycles.

Melatonin is a hormone that was discovered in 1958 by Aaron Bunsen Lerner (1920-2007), a dermatologist at Yale University in the United States. This discovery is one of many hormones that have been identified by scientists since the beginning of the 20th century. The history of endocrinology (science of hormones) began relatively late with the discovery of secretin in 1902. Between 1910 and 1930, about 30 other hormones were described, including insulin in 1921.

Melatonin is a hormone naturally produced by the pineal gland responsible for regulating the sleep cycle. During the day, the level of melatonin is very low and then increases significantly when daylight decreases. Also called the "dark hormone" or "sleep hormone," melatonin helps regulate the sleep cycle. Melatonin is now taken as a dietary supplement and is available over the counter in many countries.

Therapeutic use

Melatonin is a hormone known for its ability to regulate chronobiological rhythms and improve sleep. Secreted by the pineal gland or epiphysis, it is stimulated by the absence or decrease of light and is inhibited by exposure to light. The concentration of available melatonin tends to decrease with age, which can lead to difficulty falling asleep and insomnia. Taking melatonin in people with regular and stable sleep is of limited interest.

Melatonin is especially recommended for people who travel frequently and change time zones. An intercontinental trip may interfere with sleep cycles, for those people who often suffer from jet lag symptoms. In this case, taking melatonin can help improve sleep, both to help fall asleep and to increase sleep duration. Melatonin can also be interesting for people working at night with irregular work cycles.

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