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Benefits

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MAGNESIUM is strongly recommended when:

During a long-haul trip that does not allow you to rest properly

After an exhausting trip to recharge your batteries quickly to be operational

For various professional or private reasons, you are lacking energy and have accumulated fatigue

Ingredients and scientific evidence

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Magnesium

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MAGNESIUM citrate is a preparation of magnesium in salt form with citric acid in a ratio of 1:1 (1 atom of magnesium per molecule of citrate). This association has indeed shown the best rates of assimilation and is better tolerated. It is the solution that is regularly used for premium quality products.

Magnesium is an essential mineral: it participates in the functioning of more than 300 enzymes that are involved in energy source reactions (especially for muscles and brain). Considered by the scientists as the "energy" mineral, a lack of magnesium leads to neuromuscular hyperexcitability.

Symptoms can appear on the mental level with anxiety, irritability, morning fatigue, headaches or insomnia. They can also magnify on the muscular level with cramps and for example exaggerated tiredness during effort.

Although magnesium is essential for the functioning of the body, its intake is often well below the recommended level. Magnesium is found in certain types of foods including nuts, seeds, fruits, vegetables and whole grains.

French Maritime Pine Bark - Pycnogenol®

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French Maritime Pine Bark is an the outer pine bark of Pinus pinaster a mono-species growing in Southwest France in Les Landes de Gascogne, also France’s largest forest. The use of pine bark was first documented back in 1535, during Jacques Cartier’s expedition to Canada the fleet lay stuck on a frozen a river for several months, lacking of fresh supplies. The members of the crew who had suffered from severe scurvy, were treated with a tea made of pine bark and needles several times a day, recommended by the Iroquois Indians. It was later discovered that besides a small content in vitamin C, pine bark contains bioflavonoids.

Pycnogenol®, as a standardized extract of pine bark, contains a combination of 65-75% proacyanidins, bioflavonoids (catechin, taxifolin) and various organic acids in naturally defined constant proportions, which offer health benefits including in circulatory health.

Pycnogenol

Ginger

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Ginger or Zingiber officinale is a widely known herbaceous plant with irregular shaped roots (rhizomes) and used as a flavoring agent or spice in food and a herbal medicine for centuries in China and India (Ayurveda) among others, to support digestive imbalances pain, heartburn, nausea, indigestion and vomiting. The most widely used in traditional medicinal practice is to promote blood circulation. Ginger consists in compounds gingerol, shogaols, zingiberene and zingerone, as well terpenes, vitamins and minerals.

How does DAILY CIRCULATION support good blood circulation and assists microcirculation?

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The support on well-being provided by Daily Circulation (Zinopin®) significantly benefits from the combined antioxidant potency delivered by all active constituents. Maqui berry, with its a high content of phenolics with considerable antioxidant capacity, may protect LDL from oxidation and endothelial cells (innermost layer of the arteries) from intracellular oxidative stress.1

Delphinol® has been ascribed after four weeks intake, showing a significant reduction of oxidized LDL (low density lipoprotein) cholesterol and F2-isoprostane in human moderately overweight volunteer smokers, compared to placebo.2

Pycnogenol® French maritime pine bark extract is known as a strong antioxidant demonstrating the potent neutralisation of free radicals in humans, beneficial activities particularly for the cardiovascular system. In one investigation, Pycnogenol® intake significantly increased antioxidant capacity of plasma, as determined by ORAC, and exerts favorable effects on human lipid profile.3

These results were confirmed by a twelve-week clinical trial including young healthy volunteers supplemented with Pycnogenol®, which indicate an increased endothelial nitric oxide synthesis, present in endothelial cells, that act on blood platelets to decrease their tendency to form aggregates.4 Thus, Pycnogenol® was shown to improve vascular function by improvement of endothelial function, enabling vessels to naturally dilate in support of a smoother blood flow.

Ginger root active constituents have been documented for their pharmacological activities including anti-platelet aggregation and vasorelaxing effects.5 Although in vitro studies demonstrate ginger compounds inhibit platelet aggregation, a systematic review of several existing human studies on the potential effect of ginger compared to placebo or baseline, reported inconsistent results.6

Furthermore, a meta-analysis on the effects of ginger reveal a significant lipid-lowering effect, in particular with a favorable effect on total cholesterol, LDL (low density lipoprotein) cholesterol and triglycerides.7

References

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1Romanucci V., et al. (2016). Bioactive compounds of Aristotelia chilensis Stuntz and their pharmacological effects. Curr. Pharm. Biotechnol., 17(6), 513-523.

2Davinelli S., et al. (2015). A randomized clinical trial evaluating the efficacy of anthocyanin-maqui berry extract Delphinol on oxidative stress biomarkers. J Am. Coll. Nutr., 34(SI):28-33.

3Devaraj S., et al. (2002). Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids, 37(10):931-934.

4Nishioka K., et al. (2007). Pycnogenol® French maritime pine bark extract, augments endothelium-dependent vasodilation in humans. Hypertension Res., 30(9):775-780.

5Liao Y.R., et al. (2012). Anti-platelet aggregation and vasorelaxing effects of the constituents of the rhizomes of Zingiber officinale. Molecules, 17, 8928-8937.

6Marx W., et al. (2015). The effect of ginger (Zingiber officinale) on platelet aggregation: A systematic literature review. PLOS One, 10(10), e0141119.

7Fakhri Z., et al. (2018). The effects of ginger supplementation on lipid profile: A meta-analysis of randomized clinical trials. J. Herb. Med., 3(3), 120-131.

Supplement facts

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Nutrition Facts

Serving size 1 vegetable capsule • Servings per container 10

AMOUNT PER SERVING

% DRV*

Maqui berry extract (Delphinol®)

100 mg

-

Ginger root extract (Zingiber officinale)

40 mg

-

French maritime pine bark extract (Pycnogenol®)

25 mg

-

*Daily Reference Value; - DRV not established

Other Ingredients

Hydroxypropyl methylcellulose (capsule shell), bulking agent: microcrystalline cellulose.

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For adults, take one vegetable capsule daily with water during a meal.

Free Of

GMO, lactose, gluten, wheat, artificial colors, flavors, or sugar added

Warning

- Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

- Do not exceed the stated recommended daily dose.

- The product should be stored out of reach of children.

- Do not use if you are pregnant or while breastfeeding.

- If you have any medical condition, consult a healthcare practitioner before taking any food supplement.

- Store in a cool and dry place.

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